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KEY PUBLICATIONS
2026
Akerman E, Capel RA, Rog-Zielinska EA, Winbo A, Aston D, Falter F, Bin Abdul Mu-U-Min R, Read MJ, Bose SJ, Swietach P, Wang J, Corbett AD, Koschinski A, Calamaio S, Melgari D, Prevostini R, Rivolta I, Ayagama T, Jenkin I, Simon JN, Fakuade FE, Pronto JR, Sharma P, Melia C, Song Q, Booth MJ, Platt FM, Lei M, Hester S, Fischer R, Voigt N, Schotten U, Verheule S, Dev A, Held M, Waring T, Galione A, Keller M, Bracher F, Zaccolo M, Terrar DA, Burton RAB. Lysosomal signaling pathways influence heart rhythm, and regulate atrial function. Cardiovasc Res. 2026 Sep 19:cvag207 (online ahead of print)
Ahmed S, Javvaji N, Hammond KL, Casin KM, Elrod JW, Holloway PM, Couch Y, Simon JN. Activation of TPC2 amplified lysosome-mitochondria calcium transfer to regulate energetic stress responses. bioRxiv [preprint]. 2026 Mar 4:2026.03.03.709381
2025
Adhikari H, Patel P, Javvaji N, Crabtree MJ, Simon JN. Declining nitric oxide bioavailability in cardiovascular aging: mechanistic insights and emerging interventions. J Cardiovasc Aging. 2025;5(4):20
Akerman EC, Read MJ, Bose SJ, Koschinski A, Capel RA, Chao YC, Folkmanaite M, Ayagama T, Broadbent SD, Ahamed R, Simon JN, Terrar DA, Zaccolo M, Burton RAB. Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP. Am J Physiol Heart Circ Physiol. 2024 Oct 1;327(4):H830-H846